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العنوان
Study of Changes in P Wave Dispersion and Duration as Predictors of Atrial Fibrillation in Patients with Dilated Cardiomyopathy /
المؤلف
Kamel, Ghada Mohamed Salah El-Dean.
هيئة الاعداد
باحث / Ghada Mohamed Salah El-Dean Kamel
مشرف / Alaa Mohamed Ibrahim
مشرف / Khaled S. M. Elmaghraby
مشرف / Tarek M. Abdel Rahman
الموضوع
Heart - Diseases. Cardiology.
تاريخ النشر
2008.
عدد الصفحات
166 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
1/1/2008
مكان الإجازة
جامعة المنيا - كلية الطب - Department of Cardiology
الفهرس
Only 14 pages are availabe for public view

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Abstract

The main findings in this series of 33 patients with DCM when compared to 30 age and sex matched healthy controls in EI Minia University Hospital between June 2006 to October 2007 were:
1) Surface and SAECG data: Patients with DCM showed significantly increased HR., maximum and minimum duration of P wave in surface ECG, prolonged PPduration in SAECG, and increased P-dispersion.
2) Echocardiographic data: Patients with DCM showed significantly depressed left ventricular and left atrial ejection fraction, with a significantly increased left atrial maximum & minimum volume, and increased left atrial volume at onset of P wave in ECG, while there was no significant difference in left atrial active emptying fraction or total atrial reservoir fraction.
3) Correlation of P-duration SAECG to demographic and echo-data: Patients with DCM showed significant positive correlation between P duration SAECG and LAMX volume, LAMN volume, and LA VP; significant negative correlation between P·duration SAECG and both L VEF and LAEF; while they showed no significant correlation between p-duration and age, LAAEF and T ARF.
4) Correlation of P-dispersion to demographic and echo data: Patients with DCM showed significant positive correlation between P-dispersion and LAMX, LAMN volume, and LA VP; significant negative correlation between P dispersion and both L VEF and LAEF; while they showed no significant correlation between p dispersion and age, LAAEF and TARF.
5) Effects of severity of LV systolic dysfunction on P-dispersion and PPduration SAECG: Patients with severe DCM (LV EF<25%) showed significantly prolonged P-duration SAECG and increased P-dispersion compared to those with less severe form of the disease (L VEF2:25% ).
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mary and Conclusion
In our study, although both P-wave duration and P-dispersion were found to be creased and although they were associated with increased LA volume and , reased LA and L V function in patients with DCM, there was no long-term follow to evaluate their clinical significance as predictor of AF in this particular group of
tients. There were no documented episodes of AF in our patients to study the actual edictive power of these fmdings. This may be due to the absence of long-term
!low up, the presence of few (6) patients with severe disease or the concomitant use f medication that prevent AF. Clearly, further prospective studies which include JI’ger series including more patients with severe disease and long-term follow-up auld be conducted to further clarify the clinical utility of increased P-duration, P-
~spersion, LA volume and decreased LA and LF systolic function in patients with )cM.
CONCLUSION
The increased p-wave duration and p-wave dispersion were significantly