الفهرس | Only 14 pages are availabe for public view |
Abstract A total of two hundred (200) patients were included in this study. (114) patients had cerebrovascular ischemia (group 1), (45) patients had cardiovascular ischemia (group 2) ,and (41) patients had cerebrocardiovascular ischemia (group 3). All were selected from patient admitted to the Insurance Hospital from (4-2010) to (10-2010). The term stroke is applied to a sudden focal neurologic syndrome, specifically the type caused by cerebrovascular disease (rather than hemorrhage, tumor…etc) (Johnston, 2002) Certain risk factors increase the incidence of cerebrocardiovascular ischemia and its complications such as old age, male gender,smoking, hypertension, diabetes, hyperlipidaemia, oral contraceptives, hyperuricemia and positive family history (Shaper et al., 1991) Migraine is a complex neurological disease with a genetic background. Headache is the most prominent and clinically important symptom of migraine (Messlinger, 2009). In this study, clinical risk factors with a special emphasis on migraine were studied in the three groups. We found highly statistical significance between the three studied groups in life pattern changes before the attack such as changes in sleep rhythm, stopping or decrease smoking , dietary habits changes , mood changes and activity and exercise changes (p <0.007)&this result may indicate the presence of prodromal stage in cerebrocardiovascular ischemia . In this study , there was insignificant statistical difference in transient ischemic attack , hypertension , diabetes mellitus between the three studied groups . This suggest the importance of these risk factors in the three studied groups , so we need to study these groups with control healthy groups. There was highly significant statistical difference of ischemic heart disease , arrhythmia and rheumatic heart disease between the three studied groups indicating their importance in the studied groups. The present study showed high random blood sugar, elevated white blood cells count ,cholesterol , triglyceride, low density lipoproteins levels with lower high density lipoproteins in the tree studied groups with higher level in cardiovascular ischemia. We found that transient ischemic attacks was significantly correlated with stroke severity (measured by NIHSS) and cardiac severity (measured by the ejection fraction < 40 % ) in group 1, 2 and 3 (p < 0.04). While diabetes mellitus was significantly correlated with the severity of the condition in group 1 (p < 0.01). This means that TIAs might play an important role in cerebrovascular and cardiovascular insult severity indicating its role in pathogenesis of these insults . There was insignificant statistical difference of migraine with or without aura between the three studied groups, as well as it was insignificantly correlated with the immediate outcome of cerebrovascular , cardiovascular and cerebrocardiovascular insults. This means that the migraine with or without aura showed equal importance as risk factor in the tree studied groups and might play no role in their severity or prognosis. |