الفهرس 
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Abstract
The thesis is divided into 7 parts:-Part I: is an introductory part that contains the different classes of antimicrobial agents according to their mechanisms of action in addition to the different chemotherapeutic activities of tetrazole, pyridine, pyran and pyrazole derivatives.
Part II: includes the research objectives and the major aims that direct the theoretical and practical work.
Part III: contains the theoretical discussion of the experimental work. It discusses the different possible conditions for the preparation of the desired compounds with a summarized data about the confirmation of these new compounds.
Part VI: represents the experimental part that discusses different methods and conditions that were used in this thesis for preparation of either the intermediated or final products. Moreover, the microanalytical and spectral data that confirm the structures of the newly synthesized compounds were summarized in this part.
Part V: Includes molecular modeling study of the newly synthesized compounds.
Part IV: represents the microbiological screening section which gives an idea about the antimicrobial activity of the compounds under investigation.
Part IIV: includes the list of 121 references and periodical literatures used in this thesis, covering the period of 1850-2012.