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العنوان
Epidemiological characterization of nosocomial acinetobacter spp. infections by pulsed-field gel electrophoresis /
المؤلف
Shalaby, Marwa Mostafa.
هيئة الاعداد
باحث / مروة مصطفى شلبى
مشرف / مينا سامى مسيحة
مشرف / اسماء محمد شاهين
مشرف / سهير سعيد مقلد
الموضوع
Microbiology.
تاريخ النشر
2012.
عدد الصفحات
p 212. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علم الأحياء الدقيقة (الطبية)
تاريخ الإجازة
21/11/2012
مكان الإجازة
جامعة طنطا - كلية الطب - الميكروبيولوجيا الطبية
الفهرس
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Abstract

Acinetobacter spp. emerged as a. significant nosocomial
pathogen during the late 1970s, probably as a consequence, at least in
part, of increasing use of broad-spectrum antibiotics in hospitals. Most
clinically significant isolates belong to the species Acinetobacter
baumannii or its close relatives, with many infections concentrated in
intensive care, burns or high dependency units treating severely ill or
debilitated patients. Large outbreaks can occur in such units, involving
the infection or colonization of numerous patients by specific epidemic ’)
strains of A. baumannii.
Carbapenems have previously been the treatment of choice for
infected patients, but increasing reports worldwide now describe A.
baumannii isolates resistant to all conventional antimicrobial regimens.
Data to support therapeutic use of the limited number of new
antimicrobial agents (e.g. tigecycline) with in-vitro activity against
these pathogens are still very limited.
Appropriate identification of A. baumannii and discrimination
among isolates during a nosocomial outbreak could lead to a better
understanding of the mode of spread, thus enabling better control in an
outbreak.