الفهرس 
SEQUELAE OF chrONIC KIDNEY DISEASEOnly 14 pages are availabe for public view
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Abstract
Anemia is one of the most harmful complications in patients with end stage renal disease and should be treated before its impact on morbidity and mortality of the patients.
Regular estimation of hemoglobin and iron parameters is important to proper planning of the treatment to every patient with chronic renal failure.
Erythropoietin deficiency is the most significant cause of renal anemia so it is the most important factor in the treatment in patients with end stage renal disease
Left ventricular hypertrophy, decreased cognitive function abnormal haemostatic function and impaired quality of life all are complications that can be avoided by optimal anemia management in end stage renal disease.
High level of hemoglobin over the recommended level also is associated with increasing risks of cardio vascular complications.
The aim of this study was to know the prevalent hemoglobin level and possible correlations with other parameters in hemodialysis patients in Ain Shams University Hospitals.
All patients were on 4 hours standard bicarbonate hemodialysis, thrice weekly. Dialysers were not reused. Dialysate composition was Na 130 m eq/L Cl 111 m eq/L Mg 1m eq/L, CH3CooH 3m eq/L and Ca 3 m eq/L.
In all patients we recorded full history and clinical examination stressing on hemodialysis duration, etiology of chronic renal failure and drug history and laboratory investigations including complet blood picture, serum Iron, serum ferritin, transfirrin saturation parathyroid hormone level, serum creatinine and blood urea nitrogen.
In our study we found that as regard K/DOQI guidelines for hemoglobin (11-12 gm/DL) 74% of our patients were below the recommended range 15% patients were within the recommended range and 11% of patients were above the recommended range.
Mean hemoglobin level in patients on regular recombinant erythropoietin is higher than patients not on regular (EPO) and the difference is statistically significant.
Mean hemoglobin level in patients on regular intravenous iron is higher than patients not on regular intravenous iron and the difference is statistically significant.
Mean hemoglobin level in patients on blood transfusions is lower than other patients and this may be explained by the fact that most of them were not receiving (EPO).
There was no statistically significant difference between mean hemoglobin level and mean patients ferritin; Bun; serum iron or parathyroid hormone levels.