الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 148 |  |  |
| | | from | 148 | | |
Abstract
A total number 1873 fish were used in our study, from which 1493 fish of different fish species as Tilapia species (o.spp.), Common
carp spp.(Ccarpio) and Nile catfish (Cgariepinus)and of different life
stages, where they were collected from different sources at various
localities as from El-Abbassa fish farms and from Muweis Canal at
Zagazig city at Sharkia govemorate and in different seasons of year.
They were subjected to clinical and bacteriological examination to
determine prevalance of Clostridium species infection. Typing of
C.perfringens isolates were done by using guinea pigs and PCR.
Besides, 80 apparently healthy 0. niloticus were used for studying the
pathogencity and degree of virulence of Cperfringens type A &D
isolates. Another 300 fish were used for trails for treatement of
experimentally infected fish by using antibiotics according to the
results of sensitivity test against Cperfringens type A &D isolates and
also , used to determine the effect of these antibiotics on some serum
biochemical parameters (AST , AL T and Creatinine) and on
histopathological findings of treated 0. niloticus.
The results of this study revealed that:
1. Out of 1493 examined fishes ,only 532 were clinically infected with Cperfringens at the rate of (35.63%), Nile catfish (Cgariepinus) possessed the highest infection percentage at the rate of (43.69%) followed by Tilapia spp.(o.spp.) and Common carp spp. (Ccarpio) (32.29%) and (21.23%) respectively.
) The highest infection percentage was recorded during Summer at
the rate of (41.97%)followed by Spring (38.28%), Autumn (34.77%) and finally Winter (26.45%).