الفهرس 
The facilitatory factors of seizure activity
Vitamin AOnly 14 pages are availabe for public view
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Abstract
This study was a case control, cross sectional study. It was conducted on 60 children with idiopathic epilepsy with ages rang (7.2±2.5 yrs). Their male: female ratio was 1.3:1 who were recruited from pediatric neurology clinic, Ain-shams University.
Studied patients were divided into the following groups:
1. Group (A): 20 patients (25%) newly diagnosed not receiving anti epileptic drugs.
2. Group (B): 40 patients (50%) on regular anti epileptic drugs, those will be further divided into
• Group (B1): 20 patients (25%) receiving monotherapy (11 patients (55%) on VBA acid and 9 patients (45%) on CBZ)
• Group (B2): 20 patients (25%) receiving polytherapy.
3. Group C (control). 20 apparently healthy children of age (8.9 ± 2.9 yrs) their male to female ratio was 1.2:1
So the aim of our study was to study serum level of vitamins A and E in epileptic patients and correlate it with type, duration and severity of seizure and antiepileptic drugs (AEDs) used.
Our study showed that:
• There were non significant differences as regard mean values of Vitamin A & E between males and females in patients groups.
• There were non significant differences as regard mean values of Vitamin A and vitamin E in different ages in patients groups.
• There were significantly lower mean values of Vitamin A in patient groups compared to the control group.
• There was non significant difference as regard mean values of Vitamin A in newly diagnosed group compared to the patient group on AED therapy.
• There was non significant difference as regard mean values of Vitamin A in monotherapy group compared to the polytherapy group.
• There were significantly lower mean values of Vitamin E in patients compared to the control group.
• There were significantly higher mean values of Vitamin E in newly diagnosed group compared to the patient group on AED therapy.
• There were significantly higher mean values of Vitamin E in Monotherapy group compared to the Polytherapy group.
• There were non significant differences as regard mean values of Vitamin A & E in different seizure types.
• There was non significant negative correlation between vitamin A &E and severity score.
• There was non significant negative correlation between vitamin A &E and seizure duration.
• There was non significant negative correlation between vitamin A &E and EEG grades