الفهرس 
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Abstract
Probiotics are defined as ‘‘live microorganisms, as they are consumed in adequate numbers confer a health benefit on the host’’, Probiotics may provide a number of potential health benefits mainly through maintaining good balance and composition of intestinal flora, helping to increase the body’s ability to resist the invasion of pathogens and maintain the host’s.
Therefore, probiotics have been widely used in therapeutic applications including alleviation of constipation, protection against diarrhea, control of inflammatory bowel diseases and irritable bowel syndrome reduction of hypercholesterolemia, protection against colon and bladder cancer, prevention of osteoporosis and prevention of food allergy.
So that the aim of this study is to investigate the effect of probiotics (Bifidobacterium and Lactobacillus acidophilus alone and in combinations) on biochemical and histopathological changes that may occur to rats suffering from liver toxicity by Carbon tetrachloride (CCL4).
Milk was supplemented with different levels of probiotics (Bifidobacterium and Lactobacillus acidophilus alone and in combinations). The samples (541, 624 and 793) supplement with lactobacillus acidophilus at level (108, 107 and 106) cfu/ml respectively. The samples (158 , 274 and 394) supplement with bifidobacterium lactis at level(108, 107 and 106 )cfu/ml respectively .
The samples (256, 698 and 520) suspension with the mix of lactobacillus acidophilus and bifidobacterium lactis at level (108, 107 and 106) cfu/ml respectively.
Fifteen arbitrator went on sensory evaluation of samples in terms of taste, odar, flavor and general acceptability by giving degrees as shown bottom of the evaluation from the average scores were calculated and the best acceptable level of each probiotic microorganisms were used in biological study. It was noticed that, probiotics 108 significantly more liked by panelists