الفهرس | Only 14 pages are availabe for public view |
Abstract This study was devoted to study the effect of active ingredient in plants such as 6-gingerol , thymol and carvacrol on hyperglycemic and hyperlipidaemic animals. Methods: Seventy two adult male albino rats were divided into 3 groups normal group, hyperglycemic groups and hyperlipidemic .Treatment:- rats fed on basal diet + 0.2 mg 6-gingerol, 0.4mg 6-gingerol, 0.1mg thymol, 0.2 mg thymol, 0.2 mg 6-gingerol +0.1 mg, 0.4mg 6-gingerol + 0.2 mg thymol, 3% ginger powder and 3% thyme powders. In hyperglycemia group, results showed that all treatment groups significantly (p≤ 0.01) decreased in the level of serum glucose when compared to control positive, while treatment groups significantly (p≤ 0.001) decreased in the level of serum glucose when compared to control positive in hyperlipidaemia. In hyperglycemia and hyperlipidaemia groups results showed that all treatment groups significantly (p≤ 0.001) decreased in the level of serum cholesterol as compared to control positive. In addition, 6-gingerol and thymol significantly (p≤ 0.001) caused a decrease in LDL-c, triglycerides as compared with control positive. 6-gingerol and thymol significantly (p≤ 0.01) caused a decrease in VLDL when compared with control positive. 6-gingerol and thymol caused an increase in HDL-c significantly (p≤ 0.001) as compared with control positive.0.4 mg 6-gingerol + 0.2 mg thymol were significantly lowered in serum urea and creatinine (p≤ 0.01) than control positive . 6-Gingerol and thymol significantly (p≤ 0.01) caused a decrease in ALT, AST U/L as compared with control positive. 6-Gingerol and thymol significantly (p≤ 0.05) caused a decrease in Alk.ph U/L as compared with control positive. |