الفهرس 
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Abstract
AIM: To investigate the in vitro antiviral potential of Quercus ilex (wood) extract against two RNA viruses that cause important diseases in veterinary and human medicine in comparison to extracts of green tea and pomegranate which are previously reported to have antiviral properties.
METHODS: The crude aqueous methanol extracts (CAMEs) of Q. ilex (wood), Punica granatum (rind), and Camellia sinensis (leaves), in addition to crude ethanolic extract (CEE) of P. granatum (arils) were firstly evaluated for cytotoxicity on two different cell lines, MDCK and MDBK. Afterward, evaluated for their in vitro antiviral activities against Influenza A (H9N2) virus and Bovine viral diarrhea virus (BVDV) by means of (MTT/ XTT) based colorimetric assays.
RESULTS: On MDCK cells, The Q. ilex (wood) CAME exhibited a considerable Influenza A virus inhibition percent (IP) > 97 %, which was equivalent to C. sinensis (leaves) CAME, while being less cytotoxic to these cells, and at the same time, showed more potent antiviral activity than pomegranate extracts and Amantadine on the same cell line.
On the other hand, The Q. ilex (wood) CAME anti-BVDV activity on MDBK cell line was found to be more pronounced than the other tested plant extracts on MDBK cells with (IP > 97 %) at virus dose of 100 TCID50.
CONCLUSION: Q. ilex (wood) extract shown antiviral activity, is suggesting this plant extract as a candidate for further activity-monitored fractionation to identify its active constituents.