الفهرس 
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Abstract
The aim of this study was to investigate the usefulness of a range of indices of arterial wall stiffness in the aorta and common carotid artery and the usefulness of serum Fetuin-A to clarify its potential contribution to vascular stiffness and as a biomarker of early detection of vascular calcification and atherosclerosis in children with chronic kidney disease on conservative therapy and children on hemodialysis therapy.
In the present study, serum Fetuin-A was significantly decreased in patients with CKD on conservative therapy and in hemodialysis group when compared with control group and was significantly decreased in hemodialysis patients compared to CKD patients on conservative therapy. Also, serum Fetuin-A had a significant negative correlation with serum urea and creatinine and had a significant positive correlation with glomerular filtration rate. Serum Fetuin-A had a significant negative correlation with aortic stiffness and CIMT. Also we found a significant positive correlation of aortic stiffness with duration of illness in the group of CKD on conservative therapy and hemodialysis group.
In the present study, there was a significant decrease in aortic distensibility and a significant increase in aortic stiffness in CKD patients on conservative therapy and hemodialysis group when each group was compared to control group and in hemodialysis group when it was compared to CKD patients on conservative therapy.
Our results revealed that aortic stiffness and CIMT had a significant positive correlation with CaXPo4 product in both groups.
In our study, we found CIMT increased significantly in patients with CKD on conservative therapy and in hemodialysis group when compared with control group and more in dialysis group when compared with CKD patients on conservative therapy. Also there was a significant positive correlation between CIMT and aortic stiffness.