![]() | Only 14 pages are availabe for public view |
Abstract This study highlights the incidence and different patterns of involvement of 400 cases lymphoma in the bone marrow, without discordance between BM morphology and primary site histology. Bone marrow trephine biopsy showed involvement by lymphoma in 30.25% of cases. The incidence of involvement was higher in B-cell lymphomas when compared with T-cell lymphomas and the predominant pattern of involvement was mixed. T cell rich B cell lymphoma and diffuse large B cell lymphoma had the lowest incidence of bone marrow infiltration in all the B-cell lymphomas. The highest rate of infiltration was seen in follicular lymphomas, small lymphocytic lymphoma, and hairy cell leukemia. Lower incidence was seen in HL (9.35%), whereas RS cells were rarely and hardly seen and were not mandatory for staging HL in BMB. Bone marrow aspirates had lower diagnostic value in staging NHL and no value in HL. The length of bone marrow trephine biopsy as well as bone marrow cellularity were important factors affecting detection of marrow infiltration by lymphoma. |