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Abstract Invasive MRSA occurs most frequently among patients who undergo medical procedures or have weakened immune systems. MRSA in health care settings can cause serious and potentially life threatening infections, such as blood stream infections, surgical site infections, or pneumonia (Barton M, et al., 2006). Patients who already have a MRSA infection or who carry the bacteria on their bodies but do not have symptoms are the most common sources of transmission. The main mode of MRSA transmission is from patient to patient through human hands, especially health care worker hands. Frequent hand washing with soap and water or an alcohol-based hand sanitizer is the best way to prevent the spread of MRSA, both in the hospital and in the community (Kuehnert MJ, et al., 2006). Hemodialysis patients are at increased risk of both colonization and infection with antibiotic resistant organisms (AROs) compared to the general population. However, infection control practices should not restrict a patient from dialyzing in the HD center most appropriate for them. Current practice patterns in British Columbia hemodialysis units do not provide a consistent approach to preventing and managing these organisms (Johnson LB, et al., 2009). - 151 - The aim of this current study is the assessment of prevalence of MRSA infection among regular hemodialysis patients in hemodialysis units in Menoufiya university. This study was conducted on 100 hemodialysis patients. These patients were divided into two groups: Group I: 70 end stage renal disease (ESRD) patients on regular hemodialysis in Menoufiya university hospital. (52 patients: AV fistula, 2 patients: AV graft, 12 patients: temporal catheter & 4 patients: permanent catheter). Group II: 30 end stage renal disease (ESRD) patients on regular hemodialysis in Mansheyet Sultan hospital. (23 patients: AV fistula, 4 patients: temporal catheter & 3 patients: permanent catheter). All the patients were subjected to the following: Full history taking with special emphasis on: The cause of renal failure. Number of sessions per week and duration of each session. History of infection or fever which is resistant to treatment. Any antibiotic taken for infection and its effectiveness. History of upper respiratory tract infection. History of antibiotic use. Types of vascular access. |