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العنوان
Cystatin C as A Marker of Early Detection of Renal Impairment in Type 2 Diabetes /
المؤلف
Mohamed, Hend Ahmed.
هيئة الاعداد
باحث / Hend Ahmed Mohamed
مشرف / Yasser Makram El sherbeni
مشرف / Ayman Gamil Ghobrial
مشرف / Manal Mohamed saber
الموضوع
Diabetes.
تاريخ النشر
2011.
عدد الصفحات
107 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة المنيا - كلية الطب - Clinical Pathology
الفهرس
Only 14 pages are availabe for public view

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from 134

Abstract

Group III: 18 microalbuminuric type2 diabetic patients.
A] Routine investigations that include; I-Fasting & postprandial blood glucose. 2-Glycated hemoglobin.
3- Renal function tests(serum creatinine and urea ). 4- Serum total cholesterol and triglycerides. 5-Complete urine analysis.
6-Creatinine clearance( by 24 hrs urinary collection).
B] Special investigations;
I-Microalbuminuria by ELISA (expressed as ACR)~ 2-Serum Cystatin C by ELISA.
Results of different groups were compared with each other and were summarized as follows:
• There was highly significant positive cOITelation between serum creatinine an-d age of the patients(p _value<O.Ol},.and also there was highly significant negative cOITelation between creatinine clearance and
age of the patients.
• There was significant cOITelation between cystatin C and age m aU
groups.
• Serum creatinine values were significantly differed between females
and males (p< 0.05), while no significant difference was observed for
cystatin C values ( p = 0.7) and creatinine clearance.
• There was statistically significant increase in FBG,2hrs post prandial and glycated haemoglobin in normoalbuminuric , microalbuminuric and macroalbuminuric groups when compared to control group (p-
value<O.OS).
• There was statistically significant increase ii1 serum total cholesterol and serum triglycerides in all patients groups when compared to
control group(p-vaiue<0.05).
• There wa.s statistically significant increased in serum urea m
,normoalbuminuric group and microalbumiuric group (P-value < O.OS).Also there was statistically significant increased level of serum creatinine in macroalbuminuric group when compared to controls and
normoalbuminuric group .
• There was statiscally significant decrease in creatinine clearance in
,normoalbuminuric and microalbuminuric groups (P-value<O.OS).