الفهرس 
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Abstract
Type 2 diabetes mellitus comprises an array of dysfunctions resulting from the combination of resistance to insulin action and inadequate insulin secretion. These disorders are characterized by hyperglycemia and associated with microvascular (ie, retinal, renal, possibly neuropathic), macrovascular (coronary, peripheral vascular), and neuropathic (autonomic, peripheral) complications.
Sexual dysfunction is a common problem in male diabetic patients, mainly in the form of ED. It is usually overlooked by physicians; perhaps patients might prefer that this problem be solved with the same interest as their foot is treated. In the past it was classified as neuropathic complications of diabetes rather than a macrovascular, microvascular and endocrinological process. Recently, NICE guidance on type 2 diabetes published in May 2008 recommended that men with type 2 diabetes be assessed annually for ED to provide assessment and education to address contributing factors. ED is associated with other symptoms as mood changes, decrease in recent memory, decrease in libido, and decrease in body hair. So, it is thinked that ED may also be due to hormonal changes.
The aim of our work is to assess the prevalence of hypogonadism in male type 2 diabetes, and to correlate this hypogonadism with sex hormones (TT and FT), studying the correlation between TT and FT with other clinical data (symptoms e.g. mood changes, decrease in recent memory, decrease in libido, decrease in body hair and clinical parameters as blood pressure, waist circumference) and laboratory parameters (HbA1C, HDL-C and LDL-C).
The present study included 80 male subjects aged from 30 to 60. They were classified as:
• Group (1): 40 diabetic patients.
• Group (2): 40 control non diabetic persons.
All selected individuals were subjected to the following:
Full history taking including age, duration of DM, ADAM questionnaire.
Complete clinical examination including waist circumference and blood pressure.
Laboratory investigation:
i. HbA1C.
ii. LDL-C, HDL-C.
iii. Total and free testosterone.
The results of the present study showed that:
- Diabetic patients had statistically significant higher mean values of waist circumference.
- Diabetic patients had increased prevalence of low TT but it is not statistically significant.
- Diabetic patients had higher prevalence of low FT and it is statistically significant.
- ED is a significant common problem in diabetic patients but not in non diabetic subjects.
- Other symptoms of hypogonadism as hot flushes, mood changes, decrease in libido, decrease in recent memory and decrease in body hair were not significant in both groups.
- ED had a significant negative correlatation with FT but not with TT.
- There were no correlation between duration of diabetes, type of treatment, BP, HDL-c, LDL-c and HB A1C with either TT or FT.
- There were no correlation between waist circumference and FT, but there were a negative correlation between TT and waist circumference.