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Abstract Food-drug interactions can be a major source of clients’ inconvenience and non adherence through disruptions in their daily medications schedule. Lack of knowledge of potentially significant food drug interactions can lead to poor clinical outcomes. A food may interfere with the effectiveness of a drug if the food interacts with the ingredients in the medication, preventing the drug from working properly. Nutrients in food may either delay absorption into the body or speed up elimination from the body, either or which can impact a drugs’ effectiveness. For example, the acidic ingredients in fruit juices are capable of decreasing the power of antibiotics such as penicillin. Tetracycline, another infectionfighting drug, is impacted by the consumption of dairy products. Medication is one of the most important tools in promoting health and preventing illness and disability. Health professionals, societies and associations must play an important role in spreading the message of rational use of medicines. Doctors, nurses and pharmacists are key personnel who disseminate information to increase the clients’ awareness on the proper use of medicines and how to prevent drug –drug and food drug interaction in which can help to improve clients’ compliance with their drugs The nurse has an pivotal roles with other health team members that in evaluating the effects of medications on the client’s health status, provide adequate teaching to clients regarding their medications and side effects , to ensure the adherence with their medication plan . SO, it is important that nurses should be knowledgeable about each prescribed medication and un prescribed medications, and understand the action, common adverse events and interactions with other medicines and food to help in prevention of occurrence of such interactions and avoidance of failure of clients’ treatments plan. Hence, the aims of the present study is to assess the knowledge and practices of family health nurses about food drug- interactions and to develop ,apply and evaluate food drug-interactions guideline for family health nurses in Alexandria. The study was carried out in 16 randomly selected family health centers. using the proportional allocation method 20% of the all 77 family health centers affiliated in 7 zones in Alexandria was chosen and by using the random sample method, the centers was selected from each zone. |