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العنوان
Effect of herbal drugs on liver fibrosis/
المؤلف
Nassef, Hala Talaat AbdElGhany.
هيئة الاعداد
باحث / Hala Talaat AbdElGhany Nassef
مشرف / Hanafi Ahmed Hamza
مشرف / Mohammed Osman Abd El Fattah
مشرف / Khalid Bassiouny Mohamed
الموضوع
molecular biology.
تاريخ النشر
2012 .
عدد الصفحات
700 mg :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Molecular Biology
تاريخ الإجازة
31/5/2012
مكان الإجازة
جامعة المنوفية - كلية العلوم - molecular biology
الفهرس
Only 14 pages are availabe for public view

from 154

from 154

Abstract

Liver is a vital organ play a major role in metabolism and excretion of
xenobiotics from the body. Liver injury or liver dysfunction is a major health
problem that challenges not only health care professionals but also the
pharmaceutical industry and drug regulatory agencies. Liver cell injury caused
by various toxic chemicals (certain anti-biotic, chemotherapeutic agents, carbon
tetrachloride (CCL4), thioacetamide (TAA) etc.
Chronic hepatic diseases stand as one of the foremost health troubles
worldwide, with liver cirrhosis and drug induced liver injury accounting ninth
leading cause of death in western and developing countries. Therefore, treating
liver diseases with plant-derived compounds which are accessible and do not
require laborious pharmaceutical synthesis seems highly attractive. Many plant
components are now synthesized in large laboratories for use in pharmaceutical
preparations
Nigella sativa has been used for medicinal purposes for centuries; it has
been traditionally used for a variety of conditions and treatments. Foeniculum
vulgare fixed oil has a potent hepato-protective action against carbon
tetrachloride-induced liver fibrosis in rats.
So this work aims to study the effect of herbal drugs on liver fibrosis. The
process starting by the induction of Carbon tetra Chloride (CCl4) in the liver.