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العنوان
Physiological And Biochemical Studies On Some Blood
Chemicals As Biomarkers For Liver And Renal Dysfunction/
المؤلف
Radwan, Ghada Abd Eltawab Ibrahim .
هيئة الاعداد
مشرف / Ghada Abd Eltawab Ibrahim Radwan
مشرف / Mohamed Fathy Farag Bayomy
مشرف / Ali Elsaid Yossef
مشرف / Mohamed Asem Maraay
الموضوع
Zoology
تاريخ النشر
2012 .
عدد الصفحات
700 mg :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الحيوان والطب البيطري
تاريخ الإجازة
15/5/2012
مكان الإجازة
جامعة المنوفية - كلية العلوم - Zoology Department
الفهرس
Only 14 pages are availabe for public view

from 147

from 147

Abstract

The main purpose of this study is to display the relationship
between levels of serum sialic acid, L-fucose as well as uronic acid and
the state of the liver and kidney, under certain experimental conditions, in
order to find whether these chemicals can be used as biological markers
in some cases of liver and kidney diseases. Therefore, the conventional
parameters indicating liver and renal functions have been also determined
under the same experimental conditions. The present study has been
extended to investigate and analyze the new suggested chemical markers
in blood of human especially those suffering from liver cirrhosis, virus C
infected subjects and those suffering from renal failure.
The experimental animals were divided into six groups, ten rats in
each group as following:
G1: Animals of this group received 0.4 ml olive oil intraperitoneal
injection (i.p.) on day 1 and day 7 of the experiment and served as control
group for G2 group.
G2: Each rat of this group received single dose of CCl4 (CCl4+ olive oil
in 1:1 ratio: 2 ml/kg body weight) (i.p.) on day 1 and day 7 of the
experiment.
G3: Each rat of this group received 0.4 ml olive oil (i.p.) on day 1, 7 and
day 14 of the experiment and served as control group for G4 group.
G4: Animals of this group received single dose of CCl4 (CCl4 +olive oil
in 1:1 ratio: 2 ml/kg body weight) (i.p.) on day 1, 7 and day 14 of the
experiment.
G5: Animals of this group received sterile saline solution only (i.p.) for 8
consecutive days, and served as control for G6 group.
Summary and Conculsion
- 111 -
G6: Animals received gentamicin sulphate (100 mg/kg body weight)
(i.p.) once daily for 8 consecutive days