الفهرس 
Autoimmune disordersOnly 14 pages are availabe for public view
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Abstract
everal lines of evidence suggest a relationship between
thyroid autoimmunity and the allergic response .
First , IgE as well as IgG and IgM deposit in some
Graves’ thyroid tissue and occular muscles of hyperthyroid Graves’
disease . Second , associations have been reported between
recurrence of hyperthyroid Graves’ disease and allergic rhinitis of
pollen allergy . As well as between thyroid autoantibodies and
chronic urticaria or angioedema .Third , mRNA levels for
interleukin-4 ( IL-4 ) , a switch factor for IgE production , are
elevated in thyroids of Graves’ patients with high titers of
thyroid peroxidase ( TPO ) autoantibodies and in some
Hashimoto’s thyroids. Further, some TSH receptor specific T-cell
clones from a Graves’ patient secreted TH2 cytokines including IL-4.
The aim of our study is to investigate the possible
participation of immunoglobulin E (IgE ) and thyrotropin receptor
antibodies (TRAb) in the process of Graves’ disease and atopy,
respectively.
Our study was conducted on 70 subjects 31 of them were males
and 39 of them were females. Their ages ranged from 20-42 years old
. They are divided into 3 groups:
Group Ct: included 10 healthy subjects (as a control group).
Group At: included 30 patients with newly diagnosed atopy.
This group was further subdivided into :
Group Ata included 10 patients with skin allergy .
Group Atb included 10 patients with allergic rhinitis.
Group Atc included 10 patients with bronchial asthma .
Group Gr: included 30 patients with newly diagnosed Graves’
disease .This group was further subdivided into.