الفهرس 
PROSTAGLANDINSOnly 14 pages are availabe for public view
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Abstract
The synthetic prostaglandin, misoprostol (PGE1
analogue), has largely replaced all other techniques for
pregnancy termination particularly in the second trimester
because of its efficacy, safety, cost, easy to use and easy to
store properties. There were series reported a higher incidence
of uterine rupture and major hemorrhage in women with prior
caesarean scar as compared to women with unscarred uteri
following various techniques of mid-trimester pregnancy
termination. The safety profile of misoprostol as abortifacient
or labour-inducing agent (after 20 completed weeks of
gestation) in women with a Caesarean scar is yet to be
established. Although case reports of uterine rupture have been
published with both scarred and unscarred uteri, several other
studies have shown misoprostol to be a safe agent for use in
post-Caesarean pregnancies.