الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Cd is toxic to a number of tissues including testis, prostate gland,
liver, kidneys, and lung. It is classified by IARC as category I
carcinogen. Testis is the major target for acute Cd toxicity in
experimental animals. The major mechanisms involved in Cd
carcinogenesis are aberrant gene expression, inhibition of DNA
damage repair, inhibition of apoptosis and the induction of oxidative stress.
AGE is an alternate source of fresh garlic which is odorless and
richer in antioxidants that was found to be safe and effective in
providing health benefits. It has been found to protect DNA from damage.
The present study was conducted to investigate the effect of AGE
as an antidote against the toxic
immunity, genotoxicity, male
examination of different organs.
In the present study, one hundred male albino rats were randomly
distributed into four groups each of 25. The first group was used as
negative control group which was administered saline orally. The
second group was the positive control that orally administrated 2 gm
/kg b.wt. of AGE daily for 15 days. The third group was orally
administered 1/10 LDso of CdCl2 (7.5 mg/kg b.wt. daily for 15 days).
The fourth group was orally administrated 1/10 LDso of CdCh followed
by 2 gm/kg b.wt. of AGE daily for 15 days. Five animals were
sacrificed from each group at 24h, 3, 5, 7, and 15 days post
administration. Blood samples were collected from control and treated
rats in tubes with and without anticoagulant EDT A after scarification