الفهرس 
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Abstract
Seventy five adult male albino rats were used in the present study to
evaluate the possible curative role of a natural antioxidant (Spirulina) on
streptozotocin induced diabetes. They were divided into two main groups:
- Group I (Control group): Consisted of 45 rats. They were subdivided into three
subgroups:
• Subgroup Ia (Plain control): Consisted of 15 rats that were kept
without any treatment and served as control for all experimental
groups.
• Subgroup Ib (Sham control): Consisted of 15 rats, they received a
single intraperitoneal injection of 0.1ml of citrate buffer pH 4.5 (the
solvent which was used to dissolve streptozotocin).
• Subgroup Ic (Spirulina treated group): Consisted of 15 rats, they
received spirulina, dissolved in 1ml physiological saline in a dose of
15mg/kg body weight daily orally by gastric tube.
- Group II (Diabetic group): 30 diabetic rats were selected and divided into two
subgroups:
• Subgroup IIa (Streptozotocin treated animals): Consisted of 15 of
diabetic rats and served as diabetic control group.
• Subgroup IIb (Spirulina treated animals): Consisted of 15 of
diabetic rats. They received spirulina in a dose of 15mg/kg body
weight, dissolved in 1ml physiological saline, daily orally by
gastric tube one week after injection of streptozotocin for six
weeks.
Three, five and seven weeks after injection of streptozotocin, five rats
from each subgroup of control and diabetic groups were sacrificed.