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العنوان
Echocardiographic Assessment of the Pericardium in Children with
Treated Tuberculosis
المؤلف
Helmy Zahir,Shorouk
هيئة الاعداد
باحث / Shorouk Helmy Zahir
مشرف / Magda Yehia Hussein El Seify
مشرف / Ola Abd Elaziz Elmasry
الموضوع
Mycobacterim Tuberculosis -
تاريخ النشر
2010.
عدد الصفحات
225.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2010
مكان الإجازة
جامعة عين شمس - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

from 237

from 237

Abstract

Echocardiographic Assessment of The Pericardium in Children with Treated Tuberculosis
Introduction: Tuberculous pericarditis, is found in approximately 1% of all autopsied cases of TB and in 1% to 2% of instances of pulmonary TB .Constrictive pericarditis is one of the most serious sequelae of tuberculous pericarditis (Bongani et al., 2005).The aim of this study was to assess the prevalence of residual pericardial affection in children being treated for Tuberculosis.Methods: 20 patients with a known diagnosis of pulmonary tuberculosis following up at the Pulmonology Clinic and The Chest hospital and 15 clinically healthy children age and sex matched were evaluated. They were subjected to: Chest radiograph (postero-anterior and lateral views), 12 lead surface Electrocardiogram, Echocardiography. Results: Pulmonary infiltrates were still visible in the chest x ray of 25% of patients followed by pleural effusion in 10% of patients .ECG of patients showed higher heart rate , low voltage QRS , shorter p wave duration , longer p wave amplitude , longer QRS duration , longer T wave duration and higher QTc when compared to controls. There was no evidence of constrictive pericarditis by echocardiographic parameters yet patients showed significantly thicker pericardium than control group and residual pericardial effusion. TDI reveled higher values for Tricuspid lateral annulus peak systolic velocity (S) than controls.Patients with abnormal chest x ray findings showed higher values for Tricuspid lateral annulus peak systolic velocity (S) , lower IVRT values , increased mitral A and decreased mitral E\A ratio than patients with normal chest x ray findings.Conclusion: Although no evidence of constrictive pericarditis was found in studied patients, yet there was significant thickening of pericardium, residual pericardial effusion, early right ventricular systolic dysfunction as proved by Tissue Doppler Imaging, as well as left ventricular diastolic impairment in our patients with persistent radiological evidence of pulmonary tuberculous affection. These findings highlight the value of frequent echocardiographic assessment for long term follow up of children receiving antituberculous treatment for pulmonary TB, as the pulmonary affection itself appears to affect cardiac function