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العنوان
Biochemical Effects Of whent germ oil and/or zinc sulphate againts D-galactosamine induced hepatoxicity in albino rats\
المؤلف
Abd El Gawad,Hannaa Salah Mohammed.
هيئة الاعداد
باحث / هناء صلاح محمد عبدالجواد
مشرف / اسامه محمد احمد الفقى
مشرف / السيد المهدى
الموضوع
Biochemistry Agricultural Biochemistry Liver - Functions. D. galactosamine
تاريخ النشر
2011.
عدد الصفحات
p. 121.;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Clinical Biochemistry
الناشر
تاريخ الإجازة
11/10/2011
مكان الإجازة
جامعة بني سويف - كلية العلوم - الكمياء الحيوية
الفهرس
Only 14 pages are availabe for public view

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Abstract

The goal of the present study was to investigate the effect of wheat germ oil, zinc sulphate and mixture of them administration on body weight gain and biochemical changes of D-galactosamine cirrhotic rats. The pretreatment was applied orally by gastric intubation and daily for 1 week. Adult male albino rats (160-180 gm) were allocated for the present study.
Animal were divided into four groups:
i- Group 1 (Normal control) is given the equivalent volume of
ii- Group 2 (D-galactosamine control) is given the equivalent volume of the vehicle (distilled water and DMSO) for one week before 350 mg/kg. b. wt intraperitoneal (i.p) as single dose.
iii- Group 3 (D-galactosamine group pretreated with wheat germ oil). This group is given D-galactosamine as group 2 and pretreated orally with wheat germ oil (dissolved in DMSO; dimethylsulfoxide) at dose level of 170 mg/kg. b. wt daily for one week before D-galactosamine administration.
iv- Group 4 (D-galactosamine group pretreated with Zinc sulphate) this group is given D-galactosamine as group 2 and pretreated with zinc sulphate dissolved in distilled water at dose level of 100 mg/kg. b. wt daily for one week.
v- Group 5 (D-galactosamine group pretreated with wheat germ oil and zinc sulphate). This group is given D-galactosamine as group 2 and pretreated with wheat germ oil (170 mg/kg. b. wt) and zinc sulphate at dose level of 100 mg/kg. b. wt before D-galactosamine administration.