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العنوان
Studies on the synthesis and reactions of some pyrimidine derivatives/
المؤلف
Moussa, Fatma Moussa Ahmed
هيئة الاعداد
باحث / فاطمه موسى احمد موسى
مشرف / عبدالفتاح زكريا هيكل
مشرف / احمد حسين مصطفى
مشرف / احمد حسين مصطفى
الموضوع
Studies on the synthesis and reactions of some pyrimidine derivatives
تاريخ النشر
2011
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكيمياء
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة الزقازيق - كلية العلوم - كيمياء
الفهرس
Only 14 pages are availabe for public view

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Abstract

Abstract: theino[2,3-d] pyrimidine theione 2 was synthesized ,followed by alkylation with different Alkylating agents to afforded s-alkyl derivatives 3-5,respectively . Condensation of 2 with benzoin afforded theinopyrrolopyrimidine-5 (4H).one 6 which react with allyl bromide to give the corresponding N-allyl derivative 7. On the reaction of compound 1 with Benzaldehyde derivatives afforded theino pyrimidine derivatives 10a-c, respectively. The O –acyclonucleosides derivatives 19a-c were obtained by the reaction of 10a-c with bromobutylacetate in the presence of DMF/K2C03, respectively. All the new synthesized compounds assigned by spectral and elemental analysis data.