الفهرس 
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Abstract
The purpose of this study was to investigate the function of daily task performance of individuals with retinitis pigmentosa (RP). To quantify the relationship between clinical measures of vision and self-reports and to validate self-report questionnaire data about daily task performance with observations and measurements of actual task performance.
Twenty patients with retinitis pigmentosa were included (12 males and 8 females), ranging in age from 8 to 58 years, with a mean age of 36 years. The subjects were referred from Alexandria University Hospital over a period of 6 months.
Best corrected visual acuity was measured using the E distance visual acuity chart and was converted into a logarithm of the minimum angle of resolution (log MAR) VA scale. The contrast sensitivity was measured using the CSV-1000E contrast sensitivity device. Visual fields were performed separately in each eye using the Humphrey Field Analyzer II (Swedish Interactive Threshold Algorithm Standard 30-2 program).
Because it was statistically appropriate to analyze the data from only one eye, the eye with the better visual acuity was chosen, and if visual acuity was the same in both, an eye was selected randomly.
The self-report questionnaire consisted of 52 items, 43 of which were selected from a study by Szlyk et al. and the remaining additional items were designed to target daily activities that are potentially problematic for individuals with retinitis pigmentosa. The format of the questions was based on that of the activities of daily vision scale questionnaire developed by Mangione et al.
The functional assessment battery consisted of 16 tasks ranging from near vision activities, such as reading ordinary newspaper print, to orientation and mobility activities.
The following results were obtained
This study included 60.0% male and 40.0% female.
The right eye was selected in 45.0% and left eye was selected in 55.0% of cases.
The visual acuity in logMAR ranged between 2.2 (CF in front of the eye) and 0.1 (6/7.5), with a mean of 0.8 (6/36).
Contrast sensitivity for row A (3 cpd) ranged between 0.4-2.08, for row B (6 cpd) ranged between 0.61-2.29, for row C (12 cpd) ranged between 0.31-1.99 and for row D (18 cpd) ranged between -0.13-1.55 with a mean of 1.45±0.61, 1.31±0.51, 1.29±0.57 and 0.71±0.53 for rows A, B, C and D respectively.
The patients could detect higher contrast sensitivity levels in row A (3cpd) than that could be detected in rows B (6cpd), C (12cpd) and D (18cpd) which means that the patients detection for low spatial frequency is better than their detection for high spatial frequency contrast sensitivity.
The mean deviation (MD) of visual field ranged between -34.66 and -8.46, with a mean of -28.37± 6.60. The pattern standard deviation (PSD) ranged between 1.93 and 11.47, with a mean of 6.00±3.32.
Correlation between clinical measures of vision and functional assessment related to contrast sensitivity + visual acuity + visual field (category 1)
There were a significant correlation between clinical measures of vision and functional assessment.
The highest correlation was a negative correlation between functional assessment and the best corrected visual acuity (BCV), with a P value of (0.0001).
The correlation between functional assessment and contrast sensitivity were a positive significant correlation.
As regard the correlation between functional assessment and visual field, there was a positive significant correlation. The functional assessment was more correlated with MD with a P value of (0.0068) than with PSD with a P value of (0.024).
Correlation between clinical measures of vision and functional assessment related to contrast sensitivity + visual acuity (category 2)
There was a positive significant correlation between clinical measures of vision and functional assessment.
The highest correlation was a negative one between functional assessment and BCV with a P value of (0.0001).
Correlation between clinical measures of vision and functional assessment related to contrast sensitivity + visual field (category 3)
There was a positive significant correlation between functional assessment and contrast sensitivity rows A (3cpd), D (18cpd) and C (6cpd) with a P value of (0.015, 0.046 and 0.05) respectively. There was no correlation between functional assessment and contrast sensitivity row B (6cpd).
The functional assessment showed no correlation with the visual field.
Correlation between clinical measures of vision and functional assessment related to contrast sensitivity only (category 4)
There was a positive significant correlation between functional assessment and contrast sensitivity rows D (18cpd), A(3cpd), C (6cpd) and B (6cpd), with a P value of (0.021, 0.029, 0.037 and 0.042) respectively.
The (category 1) of functional assessment showed the highest correlation with BCV, contrast sensitivity and visual field. So this category of assessment items can be depended upon in assessing the level of difficulty in daily performance for patients with RP.
Correlation between clinical measures of vision and self assessment related to Contrast sensitivity + visual acuity + visual field (category 1)
There was a significant high negative correlation between self assessment and BCV (p=0.0001).