![]() | Only 14 pages are availabe for public view |
Abstract Cholesterol showed positive association with coronary heart disease (CHD) and mortality. Therefore the present study was carried out to investigate the effect of fig (Ficus carica L) and sycamore (Ficus sycamore) fruits in hypercholesterolemic rats as well as their chemical compositions and antioxidants. A total of 42 male albino rats weighing (110±10g) were divided in to six groups, the first group received a basal diet and served as negative control, the second group received basal diet supplemented with 2% cholesterol+ 10% animal fat and 0.25% bile salt (Hypercho- lesterolemic) as positive control. The other four groups received basal diet supplemented with hypercholesterolemic diet and (3, 5%) fig and (3, 5%) sycamore for 6 weeks. The obtained results revealed that, positive control gave a significant increased in total cholesterol (TC), triglycerides (TG), LDL-c, VLDL-c and athero-genic index (LDL/HDL), liver enzymes alanine aminotransferase(ALT) and aspartate aminotransferase (AST); significantly de-creased the concentration of serum HDL-c. However groups sup-plemented with 3, 5 % fig and sycamore decline hypercholes-terolemic decreased of TC, TG, LDL-c, VLDL-c, LDL-c /HDL-c, ALT and AST and increased HDL-c. Lowering levels of TC and LDL-C and improving level of HDL-C has been linked to a lower risk of CHD (coronary heart disease). |