الفهرس 
Helicobacter PyloriOnly 14 pages are availabe for public view
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Abstract
The present study was conducted to evaluate the association between helicobacter pylori and peptic ulcer in patients with liver cirrhosis with or without hepatocellular carcinoma.
The present study was conducted in the Department of Internal Medicine and Endoscopy Unit in Ain-Shams University Hospital A total of seventy patients were enrolled in the study and classified into:
Group I: Included twenty patients with liver cirrhosis.
Group II: Included thirty patients with liver cirrhosis and hepatocellular carcinoma.
Group III: included twenty patients with non-ulcer dyspepsia.
Patients of the studied groups were subjected to full history taking, through clinical examination, laboratory investigations, imaging techniques including abdominal ultrasound and triphasic abdominal C.T, and upper GIT endoscopy with multiple gastric biopsies for detection of H. pylori. Also serological examination was done for detection of IgG antibodies against H. pylori.
Group I included 10 (50%) males and 10 (50%) females patient there ages ranged between 35 and 65 years (52.8 + 7.1), group II included 20 (66.7%) males and 10 (33.3%) females patients there ages ranged between 45 and 63 years (55.9+4.7) and group III included 10 (50%) males and 10 (50%) there ages ranged between 45 and 60 years (53.3 +3.0).
There was no statistical significant difference as regard mean age or sex among the studied groups.
The frequency of peptic ulcer was 30% among patients with liver cirrhosis and 16.7% among patients with liver cirrhosis and hepatocellular carcinoma with no statistical significant difference between the two groups as regards frequency of peptic ulcer.
There was no statistical significant difference between endoscopic evidence of peptic ulcer, PHG and severity of liver disease (Child-Pugh class) both in patients with liver cirrhosis and patients with liver cirrhosis and hepatocellular carcinoma.
The frequency of H. pylori infection by serological method was 60% in group I, 66.7% in group II and 85% in group III. However the frequency of H. pylori by histopathological method was 60% in group I, 80% in group II and 50% in group III, with no higher percentage among patients with liver disease (group I & II) compared to group III but with no statistical significant difference between them.