الفهرس 
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Abstract
Information about the use of a continuous intravenous infusion of nitroglycerine as an antihypertensive agent in the management of severe pre-eclampsia is scarce. In the present study, intravenous nitroglycerine or oral nifedipine were administered to 40 women with severe pre- eclampsia who were being managed with MgSO4 loading and maintenance doses. Maternal blood pressure and heart rate responses, fetal heart rate responses and perinatal fetomaternal adverse effects were evaluated using classical parametric and non-parametric data analysis.An important hypotensive response was observed in both groups, although this response was greater, faster and exhibited more precision in the nitroglycerine-treated group.Heart rate also increased in both nitroglycerine and nifedipine-treated group, although the increase in the nifedipine-treated group was almost twofold that in the nitroglycerine-treated group.There was no significant change in the fetal heart rate patterns in the nifedipine-treated group but in the nitroglycerine-treated group, there was a significant decrease in the number and duration of fetal heart decelerations and a significant increase in the fetal movements.The frequency of maternal adverse effects due to the vasodilator therapy was similar in both groups and the adverse effects observed included flushing, headache, palpitations and nausea.