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العنوان
The Response to Antituberculous Drugs among Patients in Dairot Central Hospital In the Period from January 2006 to December 2009
المؤلف
Nashat Ebrahim,Nancy
هيئة الاعداد
مشرف / Nancy Nashat Ebrahim
مشرف / Laila Ashour Helala
مشرف / Samar El Sharkawy
الموضوع
Pulmonary Tuberculosis.
تاريخ النشر
2011
عدد الصفحات
192.P؛
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الرئوي والالتهاب الرئوى
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة عين شمس - كلية الطب - Chest Diseases and Tuberculosis
الفهرس
Only 14 pages are availabe for public view

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Abstract

Tuberculosis remains a major health threat, and the rapid emergence of drug resistant mycobacteria has strengthed the demand for rapid methods for detection of mycobacteria in clinical samples. As prevention of tuberculosis relies on the early detection and cure the infectious cases. current efforts are focused upon improved the rapidity of identification of M. tuberculosis, allowing prompt initiation of appropriate therapy. (Huang et al., 2001)
The data of this study collected from the records of Chest unite of Dairot Hospital, The study covered the period from 2006-2009 in order to shed some light on the epidemiological pattern of tuberculosis that can define the situation of this disease and response of tuberculous patients to treatment in Dairot city.
This retrospective study was done to review the tuberculous cases admitted to chest unite in Dairot hospital during the last four years (2006-2009) in evaluation of the reponse of tuberculous patients to treatment and the situation of this diseasein Dairot city through collection of data of the tuberculous patients from the records of the chest unite of Dairot hospital in the study period.
Data was collected and analyzed and the following was found:
The total number of tuberculous cases in the study period was 248. Females accounted for 147 (59.3%) and males accounted for 40.7%.
The incidence of tuberculosis peaked in the age group 20-29 years old (26,6%), and the least incidence as found in the age group less than 10 years old (5,2%) and by other classification of age group it was found that the highest incidence in age group 15-24 years old (22,2) and ther least incidence as found in the age group less than 5 years old(3,6).
The new cases with tuberculosis were 240 (96,8%) while the number of cases who received antituberculous treatment at least once before was 8 cases (3,2%).
Pulmonary tuberculosis accounted for most of the tuberculous cases in the study period (140 cases, 56.5%), while 108 cases had extrapulmonary tuberculosis accounting for 43,5.%.
Tuberculous cases who demonstrated positive results for direct sputum smear examination for AFB were 91 cases from 140 pulmonary cases who done sputum examination accounting for 36,7% from all cases, while 3 cases were culture-positive for AFB and accounted for 1.2 from all cases%. On discharge also only pulmonary cases done sputum analysis , 115 cases were sputum smear negative for AFB (82.1%), one case was still positive for sputum smear examination for AFB (,7%) and 24 cases were not examined for sputum smear AFB (17.2%), and from all cases 115 cases were negative accounted for (46,1%) and one cases was positive accounted for (,4%) while 132 accounted for(53,5) cases not examined because they were ethier inaccessible or had extrapulmonary .
The tuberculous cases treated with category I regimen of antituberculous drugs were 239 cases (96.5%) while 9 cases treated with category II regimen of antituberculous drugs (3.5%).
And in present it was made many comperasions between diagnosis as regard sex,age and outcome treatment.and it was found males cases showed significallity lower rate of extra-pulmonary TB than females,There was a trend of higher rate of pul positive and lower rate of extrapulm TB with higher age group.
And by made age and sex distribution among TB cases it was found higher age groups showing percentages of males when compared to lower age groups.
And by made many comperasions between outcome of treatment and type of t reatment ,other co-morbitiy,duration of treatment ,work and sex but no statistical significant data found.
In conclusion:
The most results of this study matched the results of the Egyptian National Tuberculosis control Program (NTP) during the same period as regarding the age and gender distribution, site of the disease , methods of laboratory diagnosis, patient category, treatment regimens used and results of sputum examination on discharge.
The patient recording system occasionally lacked important relevant clinical and epidemiological data e.g. radiological findings and stratification, general condition of the patient and other co_morbidity, drug side effects and modifications, surveys of the patient’s contacts and their results.