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العنوان
Prevalence of Methicillin Resistant Staphylococcus aureus (MRSA) in Ain Shams University Hospitals
المؤلف
Hussien Abdel Hameed,Ahmed
الموضوع
The chemical structures of β-lactam antibiotics benzylpenicillin and methicillin.
تاريخ النشر
2010 .
عدد الصفحات
104.P؛
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأوبئة
تاريخ الإجازة
1/1/2009
مكان الإجازة
جامعة عين شمس - كلية الطب - Tropical Medicine
الفهرس
Only 14 pages are availabe for public view

from 205

from 205

Abstract

The first strains of methicillin-resistant Staphylococcu aureus (MRSA) were reported in the United Kingdom in 1961, only about two years after the introduction of methicillin, since then, similar strains have been isolated in other parts of the world MRSA in non-hospitalized populations was first noted in the early 1980’s when saravolatz et al. described an outbreak of community-acquired MRSA infection in Detroit, primarily among intravenous drug user.
The study was conducted in Ain Shams University hospitals in the Tropical Medicine Department between December 2008 and July 2009, it included 2 groups of subjects:
Group (A): 50 patients admitted to the department.
Group (B): 50 health care workers in the hospitals.
The included subjects (of both groups), underwent full history taking, laboratory investigations, swabs from anterior nares, inoculated into special cultures for Staphylococcus aureus identification, S. aureus colonies are then subjected to methicillin susceptibility testig using cefoxitin sensitivity discs and MRSA isolates are detected according to size of inhibition zone.
The results of the study showed that MRSA was detected in 11 patients (22%) of the 50 studied patients, the next most detected organism was methicillin-sensitive S. aureus (MSSA) (10 patients, 20%), followed by Gram +ve cocci (8 patients, 16%), the least detected was Gram -ve bacilli (1 patient, 2%), methicillin-resistant S. epidermidis was not detected in any of the studied patients.
On the other hand; MRSA was detected in 2 (4%) of the 50 studied health care workers (HCWs), the most detected organism among health care workers was Diphtheroid (18 HCWs, 36%), followed by Gram -ve bacilli (8 HCWs, 16%), then MSSA (4 HCWs, 8%), the least detected was meticilline sensitive S. epidermidis (1 HCW, 2%).
Also the present study revealed that male sex, residence in a rural area, and smoking were significant risk factors for MRSA colonization.