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Abstract
In this study, we studied the role of mfVEP in evaluating cases of
ocular hypertension converting into early POAG in correlation with the
results of SAP.
It was found that mfVEP is more sensitive than SAP in detecting
early glaucomatous changes in ocular hypertension patients. Latency of
mfVEP was found to be more sensitive than amplitude. Both mfVEP
amplitude and mfVEP latency showed significant abnormal changes in
localized sectors that appeared to be normal when first tested by SAP,
but later on it became relatively significant scotoma on SAP.
On the other hand, some patients had significant abnormal
changes in mfVEP amplitude and mfVEP latency, but they continued to
have a normal SAP after follow up. This could be either that these
changes will appear on SAP but after longer period of follow up, and
then it confirms the higher sensitivity of the mfVEP. But also it can be a
false alarm of false positive test, and then this will mean a lower
specificity of mfVEP than SAP.
Clinically, mfVEP was easier for the patient to perform, as it as an
objective technique which does not need an active interaction from the
patient as compared to the subjective SAP.
This makes it easier to obtain mfVEP results from the first test
done by the patients with no need for repetition to have better learning
curve and reliable test as with SAP.
Two time‐ consuming steps were met in this study, which are the
preparation of the patient and data analysis.
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from this study, we deducted that mfVEP can be of valuable role
in early detection of glaucomatous changes in ocular hypertension
patients with normal SAP results. Patients with mfVEP changes may
need closer monitoring and follow up with more frequent SAP
examination.
Further studies about mfVEP may help for better understanding of
this new advanced technique and are recommended to complete the
evaluation of the specificity and accuracy of mfVEP.
Also, more progression of mfVEP testing machine is needed to
save time and to make data interpretation and analysis easier and more
accurate.