الفهرس 
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Abstract
In this work phytochemical, pharmacological and toxicological
studies were carried out on Eruca saliva .Petroselinum crispum and
Anethum graveolens alcoholic extract. LDso of these extracts can not be
detected. when given orally in mice. These alcoholic extracts inhibit
rabbit’s intestinal motility . Eruca sativa , extract stimulates the uterine
motility of all stages of sex cycle, while Petroselinum crispum inhibit it
in all stages of sex cycle and Anethum graveolens inhibits the uterine
motility in estrus and anestrus stages while stimulation occurs at pregnant
stage. Both tested extracts of Eruca sativa .Petroselinum crispum had a
cardiac inhibitory effect on isolated rabbit’s heart, while Anethum
graveolens had a cardiac stimulatory effect. All tested extract had
hypotensive effect when injected i.v. in anaesthetized dogs. Anethum
graveolens shown an analgesic, antipyretic and progesterone like action.
Eruca sativa has an androgenic and progesterone like actions.
Petroselinum crispum has progesterone like actions. Eruca sativa and
Petroselinum crispum possess hepatoprotective effect. All tested extracts
have antibacterial effect in vitro. Petroselinum crispum and Anethum
graveolensextracts have diuretic effect in rats. Eruca sativa extract by
prolonged administration showed an increase in body weight gain while
Petroselinum crispum and Anethum graveolens prolonged
administration revealed no changes in body weight gain. Prolonged
administration of the tested extracts in rats showed changes in the blood
criteria, serum constituents and enzymatic activities with induction of
some histopathological changes in kidney and hypremia in other organs .