الفهرس 
AbstractOnly 14 pages are availabe for public view
 |  | from | 184 |  |  |
| | | from | 184 | | |
Abstract
The study was conducted to evaluate the expected effect of powder Nigella sativa seeds as feed additive for six weeks on growth performance, blood picture , immune system and histopathology in Oreochromis niloticus (O. niloticus).The results indicated that the variable positive effects of Nigella sativa on growth performance of O. niloticus as indicated by significant increase in body weight, body weight gain, and specific growth rate. Also , there were significant increase in the total red blood cell count ( RBCs), packed cell volume ( PCV), Hemoglobin concentration (Hb) and total leukocytic count with increase the count of lymphocytes, heterophiles and monocytes. The analysis of the serum indicated a significant increase in total proteins and its fraction, ( albumin, globulin and α, β and γ globulin) the experimental period particularly in the first 3 weeks. The immunological investigation indicated a high increase in the non-specific immunostimulation as indicated with increased phagocytosis and phagocytic index. Also, activation of hemopoietic tissues and proliferation of melanomacrophage center and there were inflammatory reactions indicated by degenerative changes and necrosis . the variation of histopathological changes were relatively affected by the dose and the duration of application of Nigella sativa seeds powder ( Not excess 0.5%). And the challenge of the treated O. niloticus indicated by high protection against A. hyDROPhila infection , decrease mortality as compared with the non –treated O. niloticus.