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Abstract
In patients with coronary artery disease (CAD), LV function and volumes are important parameters for long-term prognosis. Multislice computed tomography (MSCT) allows non-invasive assessment of the coronary arteries, but the accuracy of Dual-Source 64-slice MSCT for the assessment of left ventricular (LV) function and volumes is unknown.
Aim of the work: is to evaluate the diagnostic accuracy of dual source multidetector row computed tomography (MDCT) in assessment of global and regional left ventricular (LV) function in comparison with echocardiography.
Methods and Results: A head-to-head comparison between Dual-Source 64-slice MSCT and 2-dimensional (2D) echocardiography was performed in 30 patients with known or suspected CAD. The LV ejection fraction (LVEF) was derived. The LV end-diastolic volume (LVEDV) and LV end-systolic volume (LVESV) were determined. Regional wall motion was assessed visually using a 17-segment model. A 4-point scoring system was used to assign to each segment a wall motion score:
1-normokinesia, 2-hypokinesia, 3-akinesia, 4- dyskinesia.
Two-dimensional echocardiography served as the gold standard.
An excellent correlation between MSCT and 2D echocardiography was shown for the evaluation of LVEF (r = 0.97; p < .0001). Agreement for the assessment of regional wall motion was excellent (96%, қ =0.86). MSCT agreed well with 2D echocardiography for assessment of LVEDV (r = 0.91; p < .0001) and LVESV (r = 0.98; p < .0001).
Conclusions: An accurate assessment of global and regional LV function and volumes is feasible with Dual-Source 64-slice MSCT.
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Key Words: Multislice computed tomography • left ventricular function • echocardiography
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