الفهرس | Only 14 pages are availabe for public view |
Abstract The systemic inflammatory response syndrome can be self-limited or can progress to severe sepsis and septic shock. Persons with a weakened immune system are most likely to develop sepsis, but the detrimental processes that may ultimately lead to the death of the patient are mostly caused by an exaggerated, systemic response to an infection. Infections are fought in the body by both cellular defenses, including monocytes, macrophages, and neutrophils, and humoral defenses incorporating antibodies and the complement pathways. EGDT can be summarized in the following points :- 1. Early recognition and management of severe sepsis/septic shock optimizes outcome . 2. Continuous monitoring of vital signs , pulseoximetry , and urine output and initial laboratory testing 3. Simultaneously , a source of infection should be sought 4. Empiric antibiotics should be initiated as soon as possible . |