الفهرس Only 14 pages are availabe for public view
 |  | from | 66 |  |  |
| | | from | 66 | | |
Abstract
Prostate cancer is one of the most common malignancies, affecting men, during their lifetime. Radical prostatectomy is a valid option for the treatment of the majority of cases with localized prostate cancer. Biochemical recurrence was defined as the earliest sign to predict local or metastatic progression, and was used by clinicians as a promoter to start salvage treatment.Clinical and pathological data of 733 patients managed by radical prostatectomy, by two surgeons and had their pathology recently reviewed by a single pathologist, were retrospectively reviewed and analyzed, in association with the rate of biochemical recurrence, post radical prostatectomy.A different group of patients consisting of 109 patients, had their specimens stained by chromogranin A, and the neuroendocrine cells were counted both in tumour and benign prostatic foci, aiming to study the relation of neuroendocrinal differentiation, with the rate of biochemical recurrence, post surgery .