الفهرس 
STRESS RESPONSECATARACT SURGERY ANDOnly 14 pages are availabe for public view
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Abstract
P
roviding optimal eye condition as well as minimal changes in hemodynamics, metabolic and hormonal effects during eye surgeries has always been a problem not only for the anesthesiologist but also for the ophthalmologist. In this study, we compared the effects of clonidine versus diazepam on the hemodynamics, IOP, cortisol and glucose blood levels in patients undergoing cataract surgeries under general anesthesia. Our results showed that 5 µg/kg clonidine given orally 90 minutes before induction of anesthesia is more effective than 2.5 µg/kg clonidine and both doses are more effective than diazepam 0.1 mg/kg in decreasing IOP, systolic blood pressure, diastolic blood pressure and heart rate perioperatively and in preventing deleterious increase in them associated with laryngoscopy and intubation for patients undergoing cataract extraction under general anesthesia.
During surgery, the surgeons reported that patients premedicated with clonidine with either doses showed optimal vitreous pressure while those premedicated with diazepam showed high vitreous pressure causing difficulty while performing the surgery.
However, clonidine with its both doses didn’t show significant differences in its effects on blood cortisol and glucose levels compared to diazepam.