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Abstract
with gestational age. The level in F.T. was 270.7 ± 101.1 I mg/dl while
in the PT was 258.1 ± 82.5mg/dl.
After exchange transfusion there was significant decrease in
serum levels of ferritin and iron while there was significant increase ill
lI.B.C. in both groups of neonatal hyperbilirubinernia and nconaial
hyperbilirubinemia with septicemia. Serum levels of transferrin and
ceruloplasmin were also increased after exchange transfusion in both
groups but without significant statistical difference.
Finally we can conclude that:
- Elevation of serum levels of primary antioxidants (ccrulnplasuun
and transferrin) and lowering serum levels of oxygen free radicals
(MDA as an index) after exchange transfusion indicated its
important role not only in decreasing the serum bilirubin level but
also in improving the defence mechanism against 0 FR i Ilj ury
especially in preterm neonates.
- Preterm and neonates with low birth weight are more vulnerable to
neonatal oxygen radical diseases because of their developmentally
low iron associated antioxidant proteins (transferrin).