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Abstract This study aims to study the critical thinking among senior nursing students at faculties of nursing in Port- Said and Cairo. A descriptive comparative study was used. The total sample includes 308 students in both Faculties, II S from Port- Said Faculty and 193 from Cairo Faculty. Data were collected by using The California Critical Thinking Disposition Inventory (CCTDI). It is consisted of 75 items. The study results revealed that, most of senior nursing students in both faculties were at ambivalence level of CTD. However, none of them had negative disposition. There is no statistical significant difference between levels of critical thinking in both faculties, The highest mean score of characteristics in both faculties was inquisitiveness; while, the lowest mean scores were open-mindedness and truth seeking for both faculties. Moreover, moles had higher percentages than female regarding self-confidence, systematicity, and analyticity, these differences were statistically significant. However, students had 20 years or more recorded higher percentages regarding analyticity and self-confidence this difference was statistically significant. Improve practicing of instructional methods that engorge CT, nursing staff must he model as critical thinkers and training staff and student about CT and how to practice its dispositions and skills effectively were recommended |