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Abstract
Pre-eclampsia is a pregnancy-specific syndrome.
This condition is a leading cause of maternal mortality and
is responsible for considerable perinatal morbidity and
mortality.
The aim of antepartum fetal surveillance is to identify
the hypoxic and acidotic fetus and this may prevent intrauterine
fetal death and decrease the risk of long-term adverse effects.
Doppler US offers a unique noninvasive
technology for investigating the fetal circulatory system.
There is ample evidence associating abnormal Doppler
findings with complications ofof pregnancy and an adverse
perinatal outcome.
In this study our aim was to evaluate the accuracy of
middle cerebral/umbilical artery resistance index (C/U RI) ratio
in predicting acidemia and low Apgar score at 5 minutes after
birth in neonates of women with pre-eclampsia.
We found no significant difference between cases and
control in age; parity and gestational age.where systolic blood
pressure and diastolic blood pressure were significantly higher in
cases than in control group.
There was a positive significant correlation between
Neonatal umbilical cord pH and (MCA/UA) RI ratio and a
negative significant correlation between neonatal umbilical cordAlso there was a positive significant correlation
between Apgar score and (MCA/UA) RI ratio .And a negative
significant correlation between Apgar score and RI (UA).But
there was no correlation between Apgar score and RI (MCA).
MCA (RI) / UA (RI) was more sensitive and more
specific than its two components UA (RI) and MCA (RI) in
prediction of Neonatal acidosis. Also diagnostic accuracy of
MCA (RI)/ UA (RI) was better than diagnostic accuracy of
MCA (RI) and UA (RI).
Although MCA (RI) / UA (RI) ratio showed high
sensitivity high PPV, its specificity and NPV was low inprediction of Neonatal outcome. And it was more sensitive than
UA (RI) and MCA (RI) and with higher diagnostic accuracy
than MCA (RI) and UA (RI).
In our study, MCA RI / UA RI ratio was found to be a
good predictor of bad neonatal outcome in high risk
pregnancies. Also we found that MCA RI / UA RI ratio shows
better prediction of neonatal acidemia than its two components