![]() | يوجد فقط 14 صفحة متاحة للعرض العام |
المستخلص The preterm neonates may have higher risks for serious problems during the first few days after birth. Feeding intolerance is a common problem in preterm infants resulting in a prolonged hyperalimentation which is associated with an increased risk of serious and sometimes even life threatening complications (Sekteera et al., 2002).Amylin is a 37 amino acid peptide hormone. It is a potent inhibitor of gastric motility. Also, it has neuroendocrine effects influencing glycaemic control, satiety, and long term energy homoeostasis.The present study aimed to evaluate the amylin level in preterm babies with feeding intolerance and to correlate it with different clinical variables.The study was conducted on 40 preterm neonates with gestational age < 34 wks, birth weight < 1.8 kg. They were introduced to gastric tube feeding with no clinical or laboratory evidence of sepsis. The neonates were fed every three hours (some every two hours) and the volumes increased as clinically tolerated.Neonates with gastric residual volume > 20 % of the previous fed in 2 successive feeds, with vomiting ± abdominal distension ± sluggish bowel movement were gathered in patients group (n=20)Their mean gestational age (31.2 ± 2.0) weeks, mean birth weight (1.4 ± 0.2) kg. Male /female were 13/7, 9 of them vaginally delivered and 11 were delivered by cesarean section. Neonates with no feeding intolerance were gathered in control group (n=20). Their mean gestational age (31.1 ± 1.8) weeks, mean birth weight (1.5 ± 0.4) kg. Male /female were 14/6, 9 of them vaginally delivered and 11 were delivered by cesarean section. |