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Abstract
The beauty of the reversible PVE is both the short term liver regeneration and the potential preservation of the embolized liver which may lead to great importance in clinical practice.
If embolized liver recovers after recanalization, at least three clinical outcomes would be expected.
First, reversible PVE would increase the possibilities of multi-step
strategies in the surgical treatment of malignant bilobar tumours like
colorectal metastases in order to spare non tumoral liver parenchyma.
Second in the field of the basic research topic of the authors,
reversible PVE would help to improve hepatocyte transplantation by
providing a temporary window to improve the yield of hepatocyte engraftment in recipient liver.
Finally, in living donor liver transplantation, why should it not be
expected that reversible right PVE would allow hypertrophy of the future
left liver graft in saving the right liver in the donor? Although, the
functional recovery of the embolized liver after recanalization was not
proven, the authors open a new field of future experimental research to investigate this hypothesis. (Lesurtel et al., 2008)