الفهرس Only 14 pages are availabe for public view
 |  | from | 131 |  |  |
| | | from | 131 | | |
Abstract
glaucoma is defined as a group of eye diseases characterized by pathological changes in the optic disc and typical defects in the field of vision that can be arrested or diminished by adequate lowering of the IOP.
Trabeculectomy is the most popular glaucoma filtration surgery because it provides adequate IOP control with fewer complications.
The only way to study the functionality of a filtering bleb is the IOP measurement and the clinical biomicroscopic analysis, with reference to the main microscopic grading scales (IBAGS). The clinical appearance and function of the blebs varies with regard to extent, elevation, and vascularity. So a meticulous slit-lamp examination is then very important in recognizing the signs of unfavorable bleb evolution, guiding clinicians in earlier decision-making with regard to the necessity, modality, and timing of further treatment.
Beside the clinical assessment, new morphologic diagnostic methods capable of a precise filtering bleb structural analysis, such as ultrasound biomicroscopy, laser scanning In Vivo Confocal Microscopy (IVCM) and Anterior Segment-Optical Coherence Tomography (AS-OCT) can be used for the morphologic assessment of the conjunctival, subconjunctival, and scleral features in filtering blebs after glaucoma surgery.
It was noticed that the rate of fibrosis was higher in glaucoma surgeries in young paients, in black races, with people on antiglaucoma eye DROPs for long time, in uveitec glaucoma and glaucoma secondary to diabetes.
Bleb failure remains a common problem following glaucoma filtering surgery. “Early failing/failed blebs” are categorized as those occurring within the first postoperative month. It may be associated with internal obstruction of sclerostomy, subconjunctival and/or episcleral fibrosis, or a tight scleral flap.