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العنوان
The Relationship Between Helicobacter Pylori Infection and Bronchial Asthma /
المؤلف
Soliman, Amr Hamed Mohammed.
هيئة الاعداد
باحث / Amr Hamed Mohammed Soliman
مشرف / Alaa Abd-El Salam Dawood
مناقش / Ali Zaki
مناقش / Ibrahim Boghdadi
الموضوع
Internal Medicine. Bronchial asthma. Helicobacter pylori infections.
تاريخ النشر
2010.
عدد الصفحات
103 p ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
1/1/2010
مكان الإجازة
جامعة المنوفية - كلية الطب - Internal Medicine
الفهرس
Only 14 pages are availabe for public view

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Abstract

Asthma is a chronic inflammation of the lungs in which the airways (bronchi are reversibly narrowed. Asthma affects 7% of the population,and 300 million worldwide.Christopher H. et al. 2009 Helicobacter Pylori participates significantly in the pathology of duodenal and gastric ulcer, carcinoma and lymphoma of the stomach.Moreover, mechanisms underlying HP responsibility in some extragastric diseases such as cardio and cerebrovascular diseases, may be ascribable to direct bacterial effects, systemic effects provoked by soluble inflammatory mediators released by HP, or cross-mimicry between bacterial and host antigens (Gasbarrini et al., 2002).The aim of this work is to study the relationship between Helicobacter pylori infection and Bronchial Asthma.To achieve such target,we selected 48 persons 30 asthmatic patients and 18 as a control group. Helicobacter Pylori was diagnosed with C13 UBT which is recent non invasive methods for diagnosis of HP infection.We found that there was no significant difference among the studied groups as regard age and gender (P>0.05).The mean age was 40.4 ± 10.5
years in patient group and 38.2 ± 11.6 years in control group. There was no significant difference between both groups.In patient group, there were 16 males (53.3%) and 10 14 females (46.7%). In control group, there were 10 males (55.5%) and 8 females (44.5%), with no significant difference between both groups. As regards socioeconomic level in pati ent group, there were 46.7% of low level, 46.7% of middle level and 6.6% of high level. While, in control group, there were 44.4% of low level, 38.9% of middle level and 16.6% of high level. There was no significant difference between both groups.As re
gards urea breath test, 73.3% of asthmatic patients had positive test Helicobacter +ve) (figure 1) versus 55.5% in control group. There was no significant difference between both groups Asthmatic patients were subdivided into two subgroups as regards the presence of upper GIT symptoms. Two thirds of the patients had upper GIT symptoms while the remaining third was without these symptoms The mean age was 40.95 ± 11.61 years in asthmatic patients with upper GIT symptoms and 39.62 ± 6.78 years in those without upper GIT symptoms. There was no significant difference between both groups The mean body weight was 72.45 ± 8.52 years in asthmatic patients with upper GIT symptoms and 74.5 ± 5.8 years in those without upper GIT symptoms.There was no significant difference between both groups.There was no significant difference between both groups as regards sex distribution. There were 11 males (55%) and 9 females (45%) in asthmatic patients with upper GIT symptoms and 5 males (50%) and 5 females (50%) inasthmatic patients without upper GIT symptoms.