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العنوان
Strutural Elucidation of Some New Thiadiazolines, Unsymmetrical Azines and Pyrazoles via Spectroscopic and Quantum Mechanical Calculation /
المؤلف
Zaki, Yasser Hassan.
هيئة الاعداد
باحث / ياسر حسن زكى
مشرف / عبده عثمان عبد الفتاح
مشرف / حسين محمد أحمد مصطفى
الموضوع
Pyrazoles. Azines.
تاريخ النشر
2001.
عدد الصفحات
196 P.
اللغة
الإنجليزية
الدرجة
ماجستير
تاريخ الإجازة
3/7/2001
مكان الإجازة
اتحاد مكتبات الجامعات المصرية - الكيمياء
الفهرس
Only 14 pages are availabe for public view

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Abstract

This work has been carried out to investigate: 2,3-Dihydro-l,3,4-thiadiazoles were synthesized in a good yields via reaction of hydrazonoyl halides with alky! carbodithioate. C-Aryl-2-p-nitrophenyl hydrazonoyl bromide (49, 50) reacted with each of potassium thiocyanate, potasium selenocyanate, alkyl carbodithioate, alkyl aryl dithiocarbamate or oxadiazole-2-thione in ethanolic triethylamine to afford ihe corresponding 2,3-dihydro-I,3>4-thiadiazoIes derivatives. Hydrazonoyl bromides (49, 50) reacted with malononitrile or N-arylmaleirnide to give aminocyanopyrazole and pyrrolidino[3,4-c]pyrazolines, respectively. Aminocyanopyrazole used to synthesis fused heterocycles such £5 pyrazolo[5,4-d] pyrimidines and pyrazolo[5,4-d] pyrimidino[2,3-cjtriazines, respectively. Structures of the newly synthesized compounds were elucidated on the basis of elemental analyses, spectral data (IR, 1H NMR and Mass), alternative routes whenever possible and M.O.calculation. Key words: hydrazonoyl halides, 2,3-dihydro-l,3,4-thiadiazoles, pyrazoles, p%Tazolo[5,4-d]pyrimidines and pyrazolo[5,4-d]pyrimidino[2,3-e]triazines.