الفهرس 
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Abstract
Obesity and underweight are known to be associated with sub-optimal reproductive performance but its direct effect on the outcome of assisted reproduction techniques is less clear.
Objective:
This present study aimed to perform with a systematic review of the available evidence to assess the effects of body mass index on the outcome of intra cytoplasmic sperm injection.
Material and Methods:
30couples undergoing intra cytoplasmic sperm injection program were involved in this study. 15 of patients have body mass index <25 kg/m² and other 15 patients have body mass index ≥25kg/m². The two groups were stimulated by long protocol, using decapeptyl in the previous mid luteal cycle and then stimulated by HMG by step up techniques. The dose of HMG was adjusted according to ovarian response in all groups. When at least 3 leading follicles >18mm, 10000IU of HCG were given.
Results:
The duration of induction, the number of HMG ampoules and miscarriage rate were significantly higher in women with body mass index ≥25kg/m². While the number of visualized follicles, the number of mature follicles retrieved and fertilized follicles were significantly higher in women with body mass index 25kg/m² or less. However; both groups have no significant differences regarding the pregnancy, implantation, and number of embryos transferred.
Conclusion:
Obesity is associated with lower chances for live birth after intra cytoplasmic sperm injection and with an impaired response to ovarian stimulation. So reduced body weight before intra cytoplasmic sperm injection program give a good result.
Key words:
Obesity, body mass index, infertility, intra cytoplasmic sperm injection, weight loss, PCOS.