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Abstract To assess the relation between HCV and Shistosomiasis in Egyptian patients, antibody to HCV (anti-HCV) was studied by enzyme-linked immunosorbent assay (ELISA) and by PCR in 100 patients with Schistosomiasis and egg passer in addition to 20 cases as control. For all patients, in addition to anti-HCV detection and schistosomal egg count, the following were performed: 1- Clinical history and thorough examination. 2- Routine laboratory investigation including complete blood picture, liver function tests (AST, ALT, serum biliruben, alkaline phosphatase, y glutamyi transpeptidase prothrombin time and concentration), kidney function tests (blood urea and serum creatinin). 3- Hepatitis B surface antigen (HBsAg). 4- Abdominal ultrasound. Analysis of the results of this work revealed: * The presence of anti-HCV in patient with negative HBsAg were 33% (by ELISA) and 30% (by PCR). * The main risk factors for HCV were; past history of intravenous drug use especially tartar emetic, blood transfusion or surgery but some cases still had unidentifiable risk factors. |