الفهرس 
The ThalassaemiasOnly 14 pages are availabe for public view
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Abstract
Thalassaemia is a condition in which there is a reduced
rate of synthesis of one or more of the globin chains
leading to imbalanced globin chain synthesis, defective
haemoglobin production. and damage to the red cells or their
precursors from the effects of the globin subunits that are
produced in excess.
The present study is a modest attempt to evaluate the
levels, structure and composition of liporoteins from
patients with beta thalassaemia major in comparison with
patiehts with iron deficiency anaemia and/or healthy
children.
Our study included (17) ~ thalassaemic patients age
ranged (8) years, (12) iron deficiency anaemia patients with
mean age range (2) years and also (10) age and sex matched
children, with mean age range (8) years, were included as a
control grOUp,
patients and controls were subjected to
Haemoglobin percentage
- Red blood corpuscles count
Hb electrophoresis
Serum triglycerides
- Serum cholesterol
- Serum VLDL.
Serum LDL
Serum HDL-C
- Serum apolipoprotein A1
Serum apoliprotein B
We concluded that the hypertriiglyceridaemia. increased
VLDL. hypocholesterolaemia. decreased LDL. HDL and apo-A
1
in
anaemic children IThalassaemia and iron deficiency) may be
due to:
* Diluting effect of the increased plasma volume
accompanying anaemia.
* Abnormalty in the biosynthesis and excretion
* Increased lupid consumption by red cell formation.
* Decreased lipoprotein synthesis
* Abnormalities in destribution of lipids
lipoproteins.
* Destirbance in the formation of lipoprotein lipose enzyme.
in plasma
* and/or liver desfunction associated with anaemia.