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Abstract
The hepatitis G virus (HGVlGBV-C) is recently discovered viral
agent cloned from the serum of individuals with hepatitis. Like Hey, HOY
appears to result commonly in chronic infection. The relationship of HOY
infection with liver disease and possible interaction between HGYand
known hepatitis viruses have also been estimated. However, so far no clear
link has been established between HOV and chronic liver disease.
We aimed to study HGY infection in patients with chronic renal
failure under maintenance hemodialysis, intermittent peritoneal
dialysis.personal who deal with patients (doctors ,nurses worker ) in
nephrology unit Zagazig University hospital using different laboratory
diagnostic test.
The present work included 40 patients on maintenance hemodialysis
[29 males and 11 females with a mean age of(43.6±14.7) years and ranged
from 20 to 72 years] and 20 patients on intermittent peritoneal dialysis [6
males and 14 females with a mean age of(52.9±1O.7) years and ranged
from 16 to 64 years]. And 10 persons who deal with patients on nephrology
unit [5males and 5 females with a mean age of(33.4±11.l7) years and
ranged from 24to 56 years]. In addition, 10apparently healthy individuals
[(8 males and 2 females with a mean age of(33±9.7) years and ranged from
20 to 52 years] with no previous history ofblood transfusion as a control
group.
All patients and controls were subjected to complete history taking
and some routine investigations as well as serological assays for detection
of anti-HOV-E2, HBsAg, Hlv-Ab as well as HCV-IgG using ELISA
techniques. HOV-RNA and HeV-RNA were assayed by RT·PCR.